jodi,
the simple wire remover is pretty cool. i have to say, especially getting it for free in ae 6.5 pro.
have tried it out and it works pretty well. you do have to go a couple of frames at a time and set the beginning and end of the wire remover. it is basically a setup like the basic lightning tool. you put a start point and an end point and keyframe it as time moves on. it does a fairly good job with some tests i have ran on it. if you don't want to spend the money to upgrade i would agree that the clone tool would be useful and would work pretty well, probably just as good as the basic wire remover. also- i think in some cases making a mask for the wire and then shooting a background plate is easier-just my opinion.
and you have to respect that pretty much everyone has tried to do some special effects from the matrix.
anyway good luck and post how things are going on this project.